Professor Lee Kuen-Haur Lab
Research Field
Name: Kuen-Haur Lee
- Professor, Ph.D. Program for Cancer Molecular Biology and Drug Discovery
- Joint-Appointment Professor, Master Program in Graduate Institute of Cancer Biology and Drug Discovery
- Member, TMU Research Center of Cancer Translational Medicine
- Member, TMU Research Center for Digestive Medicine
ORCID: https://orcid.org/0000-0002-6354-3315
Drug Repurposing and Cancer Molecular Mechanism Lab
Member in Our Lab
PhD students-Taiwan students (3 students)
Research direction: Investigation the roles of CRNDE in neuroendocrine-associated CRC
Research direction: Small molecule-induced endosomal escape of LNP-based siRNA by targeting the X-protein
Research direction: Genomics study for drug resistant of colorectal cancer
PhD students-International students (2 students)
Research direction: Identification the risk factors of EoCRC
Research direction: Investigation the functional role of CRNDE-regulated molecules or signaling in obesity- or diabetes-related EoCRC could provide novel insights to enhance targeted CRC cancer therapies
Research Interests
- Signal transduction of tumor biology
- Drug repurposing of cancer
- The roles of miRNAs in cancer
Related Link
- 112-115 National Science Council Integrated Project-Discussion on the regulation of pancreatic cancer metastasis and acidic microenvironment in the MIR31HG-miR-7-5p/miR-206-FXYD3 signaling pathway of early pancreatic cancer metastatic gene-FXYD3 Role (chief PI)
- 110-112 National Science Council Individual Project - Study on the role and function of the acidic microenvironment induced by extracellular matrix collagen in promoting malignant bladder tumors (co-PI)
- The fourth phase of the Cancer Research Plan of the Ministry of Health and Welfare in 2011-114 - focusing on translational medicine research on colorectal cancer (II) (co-PI)
- 112 Taipei Medical University-Ministry of Education Deepening Program-The role of targeting MIR31HG/LncHIFCAR-miRNAs-mRNAs related molecular networks in pancreatic cancer (chief PI)
- 111 Taipei Medical University-Ministry of Education Deepening Program - Research on the correlation between pancreatic cancer-specific miRNA and MIR31HG and the development of ncRNA therapies (PI)
Education
- 2009 Ph.D. Institute of Basic Medical Sciences, National Cheng Kung University
- 2004 MS. Institute of Biomedical Sciences, National Sun Yat-sen University
- 2002 B.S. Department of Marine Biotechnology and Resources, National Sun Yat-sen University
Experience
- 2023.03.14-2024.03.13 Director, Ph.D. Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University
- 2022- Professor, Ph.D. Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University
- 2022- Professor, Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University
- 2016-2022 Associate Professor, Ph.D. Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University
- 2018-2022 Associate Professor, Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University
- 2018- Director, Master Program in Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University
- 2017- Director, Ph.D. Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University
- 2012 Assistant Research Fellow, Institute for Cancer Biology and Drug Discovery, Taipei Medical University
- 2010-2012 Postdoctoral Fellow in Division of Medicinal Chemistry, Ohio State University, USA
2 Vacancies
Job Description
For international students to experience Taiwan's strengths in the field of S&T (science and technology), National Science and Technology Council (NSTC) provides the international internship program (International Internship Pilot Program, IIPP) to attract global talents. Our laboratory provides learning opportunities in the following directions:
(1) Data Mining of Biomedical and Drug Repurposing
(2) Signal Transduction in Cancer Biology Experiments
Preferred Intern Education Level
Undergraduate students, or with BSc or Master degree in life and biomedical sciences
Skill sets or Qualities
English communication skills and basic biomedical knowledge