Taipei Medical University

Professor Lee Kuen-Haur Lab

Kuen-Haur Lee
https://crdd.tmu.edu.tw/tw/teacher_detail/9

Research Field

Medicine
Introduction

Name: Kuen-Haur Lee

ORCID: https://orcid.org/0000-0002-6354-3315

Drug Repurposing and Cancer Molecular Mechanism Lab

Member in Our Lab

PhD students-Taiwan students (3 students)

Research direction: Investigation the roles of CRNDE in neuroendocrine-associated CRC

Research direction: Small molecule-induced endosomal escape of LNP-based siRNA by targeting the X-protein

Research direction: Genomics study for drug resistant of colorectal cancer 

PhD students-International students (2 students)

Research direction: Identification the risk factors of EoCRC

Research direction: Investigation the functional role of CRNDE-regulated molecules or signaling in obesity- or diabetes-related EoCRC could provide novel insights to enhance targeted CRC cancer therapies

 

 

Research Topics

Research Interests

  • Signal transduction of tumor biology
  • Drug repurposing of cancer
  • The roles of miRNAs in cancer

Related Link

Honor
  • 112-115 National Science Council Integrated Project-Discussion on the regulation of pancreatic cancer metastasis and acidic microenvironment in the MIR31HG-miR-7-5p/miR-206-FXYD3 signaling pathway of early pancreatic cancer metastatic gene-FXYD3 Role (chief PI)
  • 110-112 National Science Council Individual Project - Study on the role and function of the acidic microenvironment induced by extracellular matrix collagen in promoting malignant bladder tumors (co-PI)
  • The fourth phase of the Cancer Research Plan of the Ministry of Health and Welfare in 2011-114 - focusing on translational medicine research on colorectal cancer (II) (co-PI)
  • 112 Taipei Medical University-Ministry of Education Deepening Program-The role of targeting MIR31HG/LncHIFCAR-miRNAs-mRNAs related molecular networks in pancreatic cancer (chief PI)
  • 111 Taipei Medical University-Ministry of Education Deepening Program - Research on the correlation between pancreatic cancer-specific miRNA and MIR31HG and the development of ncRNA therapies (PI)
Educational Background

Education

  • 2009 Ph.D. Institute of Basic Medical Sciences, National Cheng Kung University
  • 2004 MS. Institute of Biomedical Sciences, National Sun Yat-sen University
  • 2002 B.S. Department of Marine Biotechnology and Resources, National Sun Yat-sen University

Experience

  • 2023.03.14-2024.03.13 Director, Ph.D. Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University
  • 2022- Professor, Ph.D. Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University
  • 2022- Professor, Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University
  • 2016-2022 Associate Professor, Ph.D. Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University
  • 2018-2022 Associate Professor, Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University
  • 2018- Director, Master Program in Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University
  • 2017- Director, Ph.D. Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University
  • 2012 Assistant Research Fellow, Institute for Cancer Biology and Drug Discovery, Taipei Medical University
  • 2010-2012 Postdoctoral Fellow in Division of Medicinal Chemistry, Ohio State University, USA

2 Vacancies

Job Description

For international students to experience Taiwan's strengths in the field of S&T (science and technology), National Science and Technology Council (NSTC) provides the international internship program

Preferred Intern Education Level

Major in medicine or life sciences 

Skill sets or Qualities

  • Ability to design experiments, analyze data, and draw meaningful conclusions using statistical and bioinformatics tools.
  • Proficiency in key laboratory techniques (e.g., PCR, Western blotting, cell culture, and next-generation sequencing) and experience with omics technologies.
  • Solid understanding of molecular biology, biochemistry, and systems biology, with familiarity in computational biology and bioinformatics.
  • Effective scientific writing and verbal communication for publications, presentations, and teamwork across disciplines.
  • Flexibility to adopt new technologies and resilience to troubleshoot challenges and innovate in evolving research environments.