Prof. Wan-Wan Lin obtained her doctoral degree in Pharmacology at National Taiwan University. She is a mentor with high enthusiasm and passion for discovering the mystery field of biology. Prof. Wan-Wan Lin's recent research focused on discovering the functional role of CASK, a scaffold protein ubiquitously expressed in various human organs. Besides, she was also involved in studying cancer metastasis, CNS, and retinal cell disease. To date, a total of 2 post-doctoral research fellows, 4 doctoral students, and 4 master students have worked in different fields under Prof. Lin's supervision. We highly welcome students or research fellows who have high passion and eagerness for biology experiments to join our lab.

We have been working on inflammation-related and innate immunity receptor-mediated signaling pathways, gene regulation, cell death, and cancer development for many years. Cell death is an important issue in controlling cellular homeostasis and biological functions. Among several types of programmed cell death, we have demonstrated the signaling cascades involved in necroptosis, parthanatos, and autophagic death. In this respect, novel functions of caspase-8 in keratinocyte differentiation and autophagy induction were reported. AMPK is a metabolism sensor, and we found it plays a crucial role in protecting microglial, skeletal muscle, and cancer cells from oxidative stress-induced cell death. At present, we are focusing on exploring the functional roles of CASK and NLRX1 in mitochondrial biology, cancer metastasis, microglial activation, retinopathy, and sarcopenia.