National Central University

Biophysics

Yi-Fan Chen
https://www.en.cme.ncu.edu.tw/products_detail/103.htm

Research Field

Physics

Introduction

Yi-Fan Chen is a professor of Chemical and Materials Engineering at National Central University in Taiwan. As a biological physicist, he is intrigued by the rich physical phenomena, including phase and critical behaviors, displayed by biomolecules (e.g., proteins, peptides and lipids) in biomembranes. He approaches these research initiatives from structural and dynamic perspectives and interpret experimental findings on the frameworks of thermodynamics and statistical mechanics. Synchrotron-based X-ray and neutron, both elastic and inelastic, scattering are his major experimental tools in attacking the research problems.

We are interested in applying the synchrotron- and neutron-based scattering and diffraction techniques to studying the structures, dynamics and phase behaviors of biological soft matter, including lipids, proteins/peptides and nucleic acids. We aim to explore how the function of matter is correlated with its structure and dynamics. This knowledge will not only advance our understanding towards the matter (which interests scientists) but also facilitate fabricating materials with desirable properties (which is a desirable achievement for engineers). Currently, our research interests include:

1. Mechanisms of the Phase Behavior Exhibited by Phospholipids and Proteins/Peptides
2. Correlations Between the Structural, Mechanical and Dynamical Properties of Biomimetic Lipid Membranes across differing length scales
3. Structural and Dynamical Studies of Polymer Nanoparticle Composites
4. Application of Neutron-based Scattering Techniques to the Studies of Biological and Novel Materials Systems

We welcome graduate and undergraduate students who are interested in these topics. We also seek potential collaborators who are interested in structurally and dynamically characterizing their biological and materials systems.


Research Topics

1. Mechanisms of the Phase Behavior Exhibited by Phospholipids and Proteins/Peptides
2. Correlations Between the Structural, Mechanical and Dynamical Properties of Biomimetic Lipid Membranes across differing length scales
3. Structural and Dynamical Studies of Polymer Nanoparticle Composites
4. Application of Neutron-based Scattering Techniques to the Studies of Biological and Novel Materials Systems


Honor

2024-2025    Ministry of Science and Technology (Taiwan) Special Topic Research Grant
2023-2024    Ministry of Science and Technology (Taiwan) Special Topic Research Grant
2022-2023    Ministry of Science and Technology (Taiwan) Special Topic Research Grant
2021-2022    Ministry of Science and Technology (Taiwan) Special Topic Research Grant
2017-2021    Ministry of Science and Technology (Taiwan) Outstanding Young Investigator Grant
2015-2017    Ministry of Science and Technology (Taiwan) Special Topic Research Grant
2014-2015    Ministry of Science and Technology (Taiwan) Special Topic Research Grant
2013-2016    Ministry of Science and Technology (Taiwan) Special Topic Research Grant (Co-PI)
2017-2020    National Central University Outstanding Research Awards
2013-2015    National Central University Outstanding New Faculty Award 
2013-2014    National Central University Outstanding Young Faculty Research Support
 


Educational Background

Ph.D. Physics, Cornell University (2011; advisor: Sol Gruner)
B.S. Chemical Engineering, National Taiwan University (2003)


1 Vacancy

Job Description

The research is expected to carry out experimental or computational (depending on this research group's need, with the the researcher's preference taken into consideration) studies in colloid and interface science, polymer, and wetting phenomena.

Preferred Intern Education Level

undergraduate or master's students

Skill sets or Qualities

The applicant has to be familiar with general laboratory techniques and demonstrate basic knowledge in laboratory safety or have experiences with molecular simulations, numerical modeling, and data analysis.