Yang Lab for Precision Medicine & Omics
Research Field
Dr. Wen-Bin Yang is an Assistant Professor at Taipei Medical University, specializing in brain tumor biology, precision medicine, and integrative omics. His research focuses on glioblastoma, mild traumatic brain injury, and intracranial aneurysms, aiming to uncover molecular mechanisms and develop innovative therapeutic strategies.
Dr. Yang’s work integrates multi-omics approaches, including genomics, transcriptomics, proteomics, and metabolomics, to understand tumor heterogeneity, therapy resistance, and the molecular basis of neurological disorders. His research is dedicated to identifying novel therapeutic targets and biomarkers that can guide personalized treatment and improve clinical outcomes.
Dr. Yang has authored numerous publications in high-impact journals and leads interdisciplinary collaborations across academia and hospitals. His commitment to translational medicine and precision health is reflected in his ongoing efforts to develop cutting-edge diagnostic tools and targeted therapies for complex neurological diseases.
The Precision Medicine & Omics Lab, directed by Assistant Professor Wen-Bin Yang at Taipei Medical University, focuses on brain tumor research and neurological diseases, with a particular emphasis on glioblastoma, mild traumatic brain injury, and intracranial aneurysms. Our mission is to leverage integrative multi-omics and precision medicine approaches to advance molecular understanding, improve diagnosis, and develop novel therapeutic strategies for these complex brain disorders.
Our Approach:
Utilizing single-cell and bulk transcriptomics, genomics, proteomics, and bioinformatics, we integrate multi-omics data to gain comprehensive insights into disease mechanisms. By combining experimental and computational methodologies, our research bridges basic science and clinical applications.
At the Precision Medicine & Omics Lab, we are committed to advancing personalized healthcare solutions and transforming molecular discoveries into tangible benefits for patients with brain tumors, traumatic brain injury, and cerebrovascular disease.
- Glioblastoma Biology and Therapeutic Target Discovery.
- Genetic and Molecular Biomarker Identification for Long-Term Symptoms after Mild Traumatic Brain Injury.
- Biomarker Discovery in Intracranial Aneurysms to Predict Stroke Risk.
- 2013/11/16 Exhibition of Excellent Poster by the 3rd International Symposium on Infectious Disease and Signal Transduction (Tainan, Taiwan) Title: Sp1-mediated microRNA-182 expression regulates lung cancer progression.
- 2019/03/24 Exhibition of Excellent Poster by the 34th Joint Annual Conference of Biomedical Science (Taipei, Taiwan) Title: Impaired DNA Damage Repair and Response Signaling by HDAC6 Inhibition as a Therapeutic Strategy for Glioblastoma.
- 2023/12/17 Best paper award by the 2023 The 16th Annual Congress of Taiwan Neurosurgical Society (Taichung, Taiwan) Title: Re-evoking CXCR7 Resuscitates Immune Checkpoint Blockade Therapy in Glioblastoma via CXCL12-NFκB-PD-L1 Axis in Glioblastoma-associated Macrophages/microglia.
- 2014/12 Ph.D. - Bioinformatics and Biosignal Transduction, National Cheng Kung University, Taiwan.
- 2009/06 M.S. – Bioinformatics, National Cheng Kung University, Taiwan.
- 2007/06 B.S. - Bioagricultural Sciences, National Chiayi University, Taiwan.
2 Vacancies
Job Description
During the internship, students will explore the role and molecular interplay of epigenetic regulation in tumor malignancy. The program also includes comprehensive training in laboratory safety, hands-on experience in basic molecular and cell biology techniques, tumor biology, and bioinformatics analysis. Interns will actively participate in regular lab meetings to enhance their data interpretation, presentation skills, and critical thinking.
Preferred Intern Education Level
BSc, MSc, or PhD in a field related to biology, medicine, or information science.
Skill sets or Qualities
Priority will be given to students with laboratory experience, especially those with research backgrounds in life sciences, medicine, or information science.