National Taiwan Ocean University

Laboratory for bioactive peptides and food analysis

Yu-Wei Chang
https://fs.ntou.edu.tw/p/412-1073-8749.php?Lang=zh-tw

Research Field

Agriculture

Introduction

Dr. Yu-Wei Chang is a professor from the Department of Food Science and also the dean of international affairs at National Taiwan Ocean University. With his enthusiasm in cooking, he has offered a course of molecular gastronomy, teaching food science youngsters to comprehend and manipulate the science behind cuisines. Dr. Chang’s research interests include food analysis, bioactive peptides, and fruit and vegetable processing. Particularly, the total utilization of food resources has been the focal point in his laboratory. Beyond research, Dr. Chang also reaches out to the community, schools, and media (TV show,) popularizing the principles and applications of food science.

  1. The underutilized food resources, such as processing by-products/co-products, are processed through advanced nutritional techniques to enhance their added value, with analysis and identification of their bioactive components
  2. Applications of Vacuum Microwave Technology
  3. Applications of High-Voltage Pulsed Electric Fields in Food
  4. Technology Development for Total Product Utilization
  5. Evaluation of Food Shelf Life


Research Topics
  1. Research on Bioactive Peptides
  • Bioactive peptides, which are peptides with specific physiological activities produced from the hydrolysis of proteins, have been identified in our laboratory from the proteins in the fish bones of tilapia processing by-products. We have discovered bioactive peptides that can exhibit blood pressure well. Other sources of peptides in various studies include mackerel cooking liquid, algal proteins, and hydrolysates from different types of gelatin.
  • Related Experimental Techniques: Protein identification, Application of bioactive peptide databases, Enzymatic hydrolysis, and Purification of bioactive peptides (ultrafiltration systems, gel filtration chromatography, etc.)

         2.  Research on Food Analysis and Food Processing

  • Using Quadrupole Mass Spectrometer, we are developing and establishing analytical identification methods for small molecular active substances (<2000 Da) in food, such as the analysis methods for amino acids and dipeptides in chicken essence.
  • Utilization of Passion Fruit Processing By-products and Analysis of Active Components.
  • Assisting in the Conduct of Level B Food Inspection and Analysis Experiments.
  • Developing Comprehensive Utilization Technology for Spear Shrimp (Products: Spear Shrimp Soy Sauce, Seafood Seasoning Powder).

         3. Applications of Microwave Vacuum Drying

  • Microwave vacuum drying is a low-temperature drying technology where microwaves cause the moisture in the sample to dissipate from the inside out, and the vacuum lowers the boiling point of the moisture. Typically, the drying temperature does not exceed 70 °C. Additionally, the drying costs and time are lower than those of freeze drying, while also preserving the nutritional components of the sample. Our laboratory is currently focused on applying microwave vacuum drying to the research of dried pineapples and composite microwave vacuum dried abalone.

Honor

1. Professor Yu-Wei Chang obtained his PhD from McGill University in Canada in 2010 and returned to his alma mater, National Taiwan Ocean University, to teach in the Department of Food Science in early 2013. Over the past 12 years, he has been engaged in teaching, research, and service in food science and technology, and has guided 50 master's students to graduation (including 6  international students and 3 exchange students from the Philippines). Graduates from his laboratory hold key positions in major food biotechnology industries and academic institutions both domestically and internationally (such as Uni-President, Cheng Feng, Chia Hwa, Nan Jiao, Da Jiang Biomedical, Guang Fu Lin, Family Mart, New Dong Yang, National Certification, SGS Taiwan, Yuan Jia Enterprises, Fisheries Research Institute, Sheng Da Pharmaceutical, Sheng Chang Pharmaceutical, Keelung Hospital of the Ministry of Health and Welfare, Derite Biotechnology, Dou's Home, Ministry of Agriculture of Indonesia, University of San Carlos in the Philippines, University of the Philippines Visayas, etc.), continuously contributing to the cultivation of food-related talent both domestically and abroad.

2. Since 2014, he has implemented and promoted the Ministry of Education's "Dream Building at Sea" and "New Southbound Dream Building at Sea" programs, recommending undergraduate and graduate students for summer internships in companies in Canada and the Philippines. To date, 32 students have benefited, receiving an average of over 500,000 NTD in subsidies each year, with a total amount reaching 3.5 million NTD over the years. Furthermore, in the years 2018, 2019, and 2020, the program was selected as a highlight project for priority funding by the review committee. Notably, one student, Chen, after completing the internship, pursued a master's degree in Canada and returned to work as a quality assurance officer at a gummy bear factory (Herbaland) in Vancouver, demonstrating the applicant's commitment to cultivating an international perspective and experience for food professionals.

3. Since teaching at National Taiwan Ocean University, he has participated in various social service activities and has received several awards for enhancing social service from the school. These include giving lectures and demonstrating molecular gastronomy techniques at science and education museums, teaching jam and kimchi making in the community, lecturing on food safety education topics for the Health Bureau and Taipei City Government, and promoting food science knowledge through media (Public Television, TVBS, and Formosa TV). Additionally, since 2018, he has continuously participated in the Ministry of Education's USR program, developing local ingredients (such as shrimp and abalone) into specialty products, using this opportunity to bridge students into enterprises and assist local manufacturers in transformation.

4. His main research focuses on the development of underutilized food resources (by-products/co-products), particularly high-protein materials (such as tilapia by-products, mackerel cooking liquid, and soy sauce residue). He aims to increase their added value through high-nutrition processing, transforming them into functional health food raw materials (for blood pressure reduction, antioxidant properties, blood sugar regulation, and anti-amnesia). In recent years, he has also invested some research energy into novel processing methods, such as the application of microwave vacuum technology to fruit and vegetable products (like bananas, pineapples, and guavas), with over 20 research results published in international journals.

5. Over the years, he has executed more than 20 projects in collaboration with the Ministry of Science and Technology, Council of Agriculture, Ministry of Education, Industrial Technology Research Institute, Ministry of Health and Welfare, Hakka Affairs Council, and industry-academia cooperation, with a total funding amount of approximately 20 million NTD. Notable industry-academia cooperation projects include "Development of Liquid Protein Products Using Plant and Animal Protein Isolates as Main Alternative Sources," "Application of Food-Grade Trace Element Preservation Technology in the Processing of Freshly Slaughtered Lamb," "Testing and Analysis of Coumarin in Pomelo, Red Grapefruit, and White Grapefruit," "Development of Fish Sauce Formulation from By-products of Salt-Tolerant Taiwan Snapper," and "Development of Products Related to Ceylon Cinnamon Using Microwave Vacuum and Vacuum Concentration Technologies and Analysis of Their Active Ingredients," with a total technology transfer amount reaching 1.2 million NTD. 6. At the "2014 Taipei International Invention and Technology Trade Show," he won second place in the Ministry of Science and Technology's negotiation competition; the exhibited technology was "Liquid Nitrogen Ice Cream" (2015 new patent number: M 508659).

 

 


 


Educational Background
/肄業學校
Graduated / Vocational school
國別
Country
主修學門系所
Department
學位
Degree
起訖年月
Duration
麥基爾大學
McGill University
加拿大
Canada
食品科學及農業化學研究所
Food Science and Agricultural Chemistry
博士
PhD
95 / 9 至 99 / 9
2006/9-2010/9
麥基爾大學
McGill University
加拿大
Canada
食品科學及農業化學研究所
Food Science and Agricultural Chemistry
碩士
Master
93 / 9 至 95 / 6
2004/9-2006/6
國立臺灣海洋大學
National Taiwan Ocean University
台灣
Taiwan
食品科學系
Department of Food Science
學士
Bachelor
85/ 9 至 89 / 6
1996/9-2000/6