Tzu-Sen Yang, PhD, is an Associate Professor and Director at the Graduate Institute of Biomedical Optomechatronics, Taipei Medical University, Taiwan. His pioneering lab integrates photobiomodulation (PBM) techniques into regenerative medicine, cellular therapy, and optical diagnostics. His research interests include nanostructured biomaterials to modulate cellular environments, with applications in cartilage regeneration, cancer treatment, and tissue engineering. Recently, Professor Yang has employed PBM to enhance extracellular vesicle release from adipose stem cells, supporting new strategies in cell therapy and cartilage repair.

Professor Yang has pioneered advancements in laser bioprinting technology, notably developing a Laser-Induced Forward Transfer (LIFT) system that uses 830 nm wavelengths for precise cell deposition. His research also focuses on optimizing micro-arc oxidation in titanium dental implants to enhance blood compatibility and bone integration. Additionally, he has created a seven-in-one microscopy platform for single-cell diagnostics, integrating Raman spectroscopy and laser manipulation, which is now used for studying antimicrobial effects, exosome characterization, and diagnostics for endometriosis.

With numerous influential publications, Professor Yang’s innovations in biomedical optoelectronics have propelled advances in optomechatronics and regenerative medicine. Supported by funding from the University System of Taipei and Taiwan’s Ministry of Science and Technology, his research contributes substantially to photonic medical technology and cellular diagnostics. Future research aims to integrate digital imaging, organ-on-a-chip platforms, and silicon photonics to expand biomedical applications further.
 

The lab, led by Dr. Tzu-Sen Yang, specializes in Photobiomodulation, Photomedicine, and Biophotonic Detection, with a strong focus on cutting-edge technologies for biomedical research and healthcare applications. Key areas of expertise include developing platforms for single-cell manipulation and detection, studying the cellular-level effects of photobiomodulation, and advancing laser-assisted cell bioprinting techniques. The lab also investigates the biophotonic effects on adipose-derived stem cells, aiming to enhance applications in cell therapy and wound care. Efforts are directed toward innovations for quicker cancer diagnosis and the creation of advanced imaging tools like the Fourier-based microscope. Equipped with sophisticated systems such as Raman spectrometry and optical tweezers, the lab integrates interdisciplinary approaches to address fundamental and applied challenges in biophotonics and regenerative medicine.