Taipei Medical University

HYDROGELS FOR TISSUE ENGINEERING LABORATORY

Chih-Hsin Lin
https://sites.google.com/tmu.edu.tw/melodylab/home

Research Field

Emerging/Other Fields

Introduction

Dr. Chih-Hsin Lin graduated with a PhD in Dentistry from National Yang-Ming University in 2016, specializing in biomaterials and tissue engineering. Following this, Dr. Lin worked as a Postdoctoral Fellow at MIT Koch Institute from 2017 to 2019, led a project focused on fabricating liver tissue with integrated vasculature using bioprinting techniques, aiming to create a high-throughput system for drug screening—a significant contribution to tissue engineering and regenerative medicine. In 2019-2020, Dr. Lin further expanded her expertise at Chang Gung Memorial Hospital in Taiwan, where, as a Postdoctoral Fellow at the Center for Tissue Engineering, they developed a 3D-printed scaffold for creating vascularized adipose tissue. Currently, Dr. Lin is an Assistant Professor at the Graduate Institute of Nanomedicine and Medical Engineering at Taipei Medical University since 2020, where her work focuses on developing novel biomaterials and utilizing 3D bioprinting technologies to engineer functional tissues for various medical applications. 

Our research program is at the cutting edge of biomedical innovation, focusing on advanced tissue engineering, 3D bioprinting, and vascular biology. Our team is dedicated to the development of photocrosslinkable hydrogels as materials for 3D tissue constructs, pushing the boundaries of regenerative medicine. By harnessing state-of-the-art 3D bioprinting technologies, the lab is advancing the creation of engineered tissues and implementing high-throughput systems for drug screening. A key focus of their work is on 3D neovascularization, with the ultimate aim of transforming therapeutic strategies and improving disease management.


Research Topics

Our research focuses on:

Photocrosslinkable hydrogels as 3D tissue construct materials 

3D bioprinting for tissue engineering applications 

High-throughput system for drug screening 

3D neovascularization


Honor
  1. Visiting fellowship from the National Science Council of Taiwan (NSC) to pursue advanced research at the Department of Chemistry, University of Oxford (2022-2023).  
  2. Postdoctoral fellowship from the NSC to study at the David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (2017-2018).
  3. Graduate Student travel grant from the NSC to participate in an international conference (9th Meeting of the Scandinavian Society for Biomaterials, Reykjavik, Iceland), May 2016. 
  4. Graduate student study abroad scholarship from NSC to study at the Department of Developmental Biology at Harvard School of Dental Medicine (2013-2014). 

 


Educational Background
2011-2016

National Yang-Ming University (Taipei, Taiwan)

PhD of Science, Department of Dentistry 

2013-2014

Harvard School of Dental Medicine (Boston, MA, USA)

Visiting Student, Department of Developmental Biology

2007-2010

 

National Taiwan University (Taipei, Taiwan)

Master of Science, Institute of Zoology

2004-2007

National University of Kaohsiung (Kaohsiung, Taiwan)

Bachelor of Science, Department of Life Science


2 Vacancies

Job Description

Key Responsibilities:

Assist in the preparation and characterization of photocrosslinkable hydrogels and bioinks

Participate in 3D bioprinting experiments, including construct design, printing, and post-processing

Conduct cell culture, viability assays, and basic biological evaluations of printed tissue constructs

Perform data analysis and maintain detailed lab records

Conduct literature reviews on relevant topics in bioprinting and tissue engineering

Contribute to weekly lab meetings and presentations

Preferred Intern Education Level

Current undergraduate or graduate student in biomedical engineering, bioengineering, materials science, or a related field

Basic knowledge of biomaterials, cell biology, or 3D printing technologies is preferred

Strong interest in tissue engineering and regenerative medicine research

Good organizational skills and ability to work collaboratively in a lab setting

Eagerness to learn new techniques and contribute to ongoing projects

Skill sets or Qualities

Skill Sets:

Basic Laboratory Techniques – Pipetting, sterile techniques, solution preparation

Cell Culture – Familiarity with mammalian cell handling and maintenance (preferred but not required)

3D Bioprinting Tools – Interest or experience in CAD software, slicers, or bioprinters (training will be provided)

Hydrogel Handling – Knowledge or interest in working with biomaterials such as GelMA, alginate, or collagen

Microscopy and Imaging – Basic use of fluorescence or light microscopy for cell/tissue observation

Data Analysis – Proficiency in Excel; familiarity with ImageJ, GraphPad Prism, or similar software

Literature Review and Scientific Writing – Ability to summarize research findings and write clearly

Computer Skills – Microsoft Office, Google Workspace; any experience with Python or MATLAB is a plus