National Chung Hsing University

Drug Design and Chemical Biology Core Lab

Ming-Hon Hou
https://mhholab712.wixsite.com/mhholab/members

Research Field

Medicine

Introduction

Ming-Hon Hou received his Ph.D. in Biochemical Sciences from National Taiwan University. He did his postdoctoral research at the Academia Sinica and continued his research in drug design and biophysics at the National Chung Hsing University in Taiwan. He is a Distinguished Professor at the Institute of Genomics and Bioinformatics, National Chung Hsing University, and jointly appointed as Adjunct Faculty of Molecular and Biological Agricultural Sciences program of the International Graduate Program at Academia Sinica, Taiwan. His research interests cover a wide range of structural biology and drug development topics, including protein structure, unusual DNA structures, DNA–drug and protein-drug interactions.​

In order to solve the health problems that human beings are facing today, our research focuses on the development of novel drugs against several important infectious diseases, genetic diseases, and cancers. Our major research projects include:

  1. Development of antiviral drugs targeting the nucleocapsid protein against emerging viruses.
  2. Development of anticancer drugs targeting DNA or RNA.
  3. Development of diagnostic tools for genetic diseases associated with unusual DNA structures.


Research Topics
  1. DNA-binding drug design
  2. The study of function and structure of viral nucleocapsid protein
  3. Antiviral drug development

Honor
  1. 2022 "National Innovation and Excellence Award" in recognition of continuing innovations and advancements in R & D to broad spectrum antiviral drug targeting nucleocapsid protein against coronaviruses (2022)
  2. 17th National Innovation Award for development of broad spectrum antiviral drug against coronaviruses (2020)
  3. Ministry of Science and Technology (MOST) Outstanding Research Award (2020)
  4. Four years project for Excellent Junior Research Investigators from Ministry of Science and Technology (2020)
  5. Three years project for Excellent Junior Research Investigators from Ministry of Science and Technology (2017)
  6. The Young Scholars’ Creativity Award from the foundation for the advancement of outstanding scholarship (2015)
  7. Excellent Young Scholar Award from the Chemical Society Located in Taipei (2015)
  8. Young Scientist Research Award, Tien-Te Lee Biomedical Foundation (2015)

Educational Background

Ph.D., Institute of Biochemical Sciences, National Taiwan University