National Health Research Institutes

Liu Lab

Han-Hsuan Liu
https://nhri-hhliulab.webnode.tw/

Research Field

Biology

Introduction

Han-Hsuan is a neuroscientist passionate about basic science and enthusiastic to apply our findings to translational medicines and benefit patients and the whole society. She earned a B.S. degree in Life Science and completed her Ph.D. training in Dr. Hollis Cline's lab at the Scripps Research Institute (TSRI) in La Jolla, California, USA. Before joining the Center for Neuropsychiatric Research at the National Health Research Institutes in 2023, she was a postdoc working in Dr. Yuh-Nung Jan's lab at UCSF. Her long-term goal is to provide fundamental insights into the field of neurodegeneration and aging with the hope of preventing neurodegeneration, improving the diagnosis of neurodegeneration, and developing drugs promoting neural recovery from injury and diseases.

 

We have 3 talented research assistants and one co-mentored student (primarily based in Dr. Eric Hwang's lab at NYCU) in our lab. Each person is leading 1-2 projects and shares their expertise to help each other. We combine a variety of novel approaches to search for candidate genes regulating dendrite degeneration and repair during neurodegeneration. Our long-term goal is to provide fundamental insights into the field of neurodegeneration and aging which can guide us to design strategies to prevent neurodegeneration, diagnose neurodegeneration early, and promote neural recovery from injury and diseases.


Research Topics

Dendrite pathology is clinically relevant to traumatic brain injury, strokes, and many forms of neurodegeneration but the underlying mechanisms are largely unknown. Our research goal is to uncover the underlying mechanisms of dendrite degeneration and repair in the context of diseases, injury, and aging. Currently, there are three main directions that we are pursuing:

1. What genes are involved in dendrite degeneration and regeneration?

2. How can we restore impaired neuronal functions?

3. How is aging affecting dendrite degeneration and repair?

In addition to the directions mentioned above, we have several side projects trying to understand how the environment modulates and challenges our nervous system. Come talk to us to learn more!


Honor
2020 Conference Travel Award, 18th International Symposium on Neural Regeneration
2016 – 2017Fellowship, Helen Dorris Foundation, TSRI
2015Conference Travel Award, Dorris Neuroscience Center, TSRI

Educational Background
2011 – 2017Ph.D., Biology track, The Scripps Research Institute, La Jolla, CA, USA (TSRI)
2006 – 2010B.S., Life Science, National Yang-Ming University, Taipei, Taiwan, (NYMU)