Kaohsiung Medical University

Kaohsiung Municipal Siaogang Hospital medical laboratory

Szu-Chia Chen
https://www.kmsh.org.tw/web/wwwkmhk/affairs/index.asp?deptcode=7100

Research Field

Medicine

Introduction

Name: Szu-Chia Chen  

Education: 

  1. 1994-2001 M.D. Kaohsiung Medical University 
  2. 2014-2018 PhD Graduate Institute of Clinical Medicine, College of Medicine, Kaohsiung Medical University

Medical License: 2001 National Medical Board of Taiwan 

2004 Specialist of Internal Medicine 

2006 Diplomate, subspecialty in Nephrology 

Postgraduate Training: 2001-2006 Residency training, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University 

Principal Clinical Service Responsibility: 

2006 Attending Physician, Department of Internal Medicine, Kaohsiung Municipal Hsiao-Kang 

2012 Assistant Professor, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan

2015 Associate Professor, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan

2018 Professor, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan

Now affiliation

  1. Ph.D. Program in Environmental and Occupational Medicine, Kaohsiung Medical University
  2. Research Center for Precision Environmental Medicine, Kaohsiung Medical University

Our hospital has a medical laboratory and has set up management methods, and has set up dedicated researchers with master's level or above to manage it; colleagues in the hospital can fill out an application form for the use of instrument space to apply for use, and use an access control system to manage access. 

The laboratory has sufficient space and is equipped with various basic instruments as shown in Table 1 below. The instruments are kept and used in good condition and have records. Budgets are also being prepared for the replacement of old instruments and the purchase of new instruments. Experimental projects that can be carried out include basic meristem technology operations, cell culture, enzyme immunoassay, Western blotting, etc.

Table 1. Main laboratory instruments and equipment

instrumentsquantityinstrumentsquantity
High speed micro refrigerated centrifuge1Fully automatic enzyme immunoassay analyzer (Elx808)1
Small liquid nitrogen insulation barrel D-1000W1-30 degree low temperature freezer1
Hot air circulation thermostat (DK-500)1Colloidal imaging system1
Carbon dioxide incubator RC03000T-51Specimen pre-processing system1
Western Blotting Kit1Freezer1
Inverted biological microscope CKX311Ultrapure water making machine1
CKX31 photo kit1-80 degree low temperature freezer1
Nucleic acid multiplier (TAKARA TP600)1Microplate cleaner1

 


Research Topics

My clinical specialties are in cardiology, nephrology, and endocrinology. My research interests lie in these clinical specialties and include assessments/evaluations of cardiovascular function, renal function, and metabolic syndrome, through general health examinations, clinic research study design, intervention study design, clinic trials, and epidemiologic research. I have participated in and directed over 10 research projects funded by the Taiwan National Science Council. Casually related to the proposed study, I have 20+ peer-reviewed publications on the prognosis of patients with chronic kidney disease, in relation to their Type 2 Diabetes (T2D) status, metabolic syndrome, and/or cardiovascular functioning. The publications document assessments and analyses of metabolic and endocrine outcomes. I have published extensively (60+ peer-reviewed articles) in the areas of echocardiography, ankle-brachial index, brachial-ankle pulse wave velocity, and heart rate variability, from research studying cardiovascular functioning in patients with chronic kidney disease and high cholesterol. Recently, I have been directing a number of research projects funded by the Taiwan National Science Council for assessing advanced therapies and treatments for peripheral vascular disease in hemodialysis and identifying Audicor associated clinical outcomes in high-risk populations. 

As an internist, I have collaborated with endocrinologists on research concerning the complications of T2D and metabolic syndrome on the renal and cardiovascular systems. Through collaborations, I have affiliations with the Division of Endocrinology and Metabolism at the Kaohsiung Medical University Hospital. The Division includes a Research Center specializing in metabolic disorders, obesity, and diabetes, which has equipment of the highest quality for analysis of metabolic outcomes and biomarkers. I have further collaborated with environmental and occupational epidemiologists, and industrial hygienists, on exploring the influence of air pollution, heavy metals, and phthalates on both occupational workers and the general population. On these projects, I’ve participated in biomarker analysis, study design, and data interpretation from both clinical and scientific parts. Such collaborations have led to 10+ publications in exposure assessments and cardiovascular, renal, and metabolic disorder outcomes. These research activities directly align with the goal of the proposed study, examining the health effects of welding metals on insulin homeostasis outcomes in welders. 

I am part of the Occupational and Environmental Medicine group at Kaohsiung Municipal Siao-Kang Hospital (KMSH), one of the hospitals in the Kaohsiung Medical Hospital health care system. KMSH is the major hospital in Taiwan providing health care for occupational workers in industrial and manufacturing sectors. Besides, I am the professor of Ph.D. Program in Environmental and Occupational Medicine, Kaohsiung Medical University, and Research Center for Precision Environmental Medicine, Kaohsiung Medical University. 


Honor
  1. Outstanding Paper Award for the Paper Report at the Annual Meeting of the Society of Nephrology, Outstanding Staff in Research Papers at Siaogang Hospital, Outstanding Research Teacher at Kaohsiung Medical University

Educational Background
  1. 1994-2001 M.D. Kaohsiung Medical University 
  2. 2014-2018 PhD Graduate Institute of Clinical Medicine, College of Medicine, Kaohsiung Medical University