My name is Yung-Chia Chen. I have held Ph.D in Anatomy and Cell Biology and graduated from National Taiwan University in 2008. After graduation, I worked as a postdoctoral researcher at National Taiwan University and the Cardiovascular Research Center of National Cheng-Kung University. I am the full professor since Aug. 2022, in the Department of Anatomy, School of Medicine, College of Medicine, Kaohsiung Medical University. My academic expertise is anatomy, histology, embryology, and cell biology. My research focuses on the use of natural non-toxic plant extracts or compounds from plants to find the complementary therapy for cancer, metabolic dysfunction, inflammation, and endocrine-related disorders. I actively apply and implement the funding projects, and also, to the develop science collaborations. In addition to Kaohsiung Medical University projects, the projects that I have participated in, including the Ministry of Science and Technology, the Ministry of Agriculture and the Ministry of Education projects . So far, 34 SCI papers and 18 symposium poster papers have been published. 

Being a corresponding author, I have won 3 outstanding papers award from KMU, and has published 1 paper with an impact factor over 5 (2017) and 1 paper with impact factor over 6 (2021). From 2022 to 2024 Jan. I was invited to be a guest editor on the Special issue: “Drug discovery Targeting the MAPK-ERK pathway”(https://www.mdpi.com/journal/pharmaceuticals/special_issues/MAPK_ERK_pathway) and “Discovering Novel Drugs from Plants" (https://www.mdpi.com/journal/pharmaceuticals/special_issues/68SY805ZO3) in the journal of Pharmaceuticals.

Our laboratory is equipped with advanced facilities and expertise in a wide range of experimental techniques, enabling comprehensive investigation into cellular and molecular processes. These include:
Cell Culture: We maintain and manipulate established cell lines as well as primary cell cultures to model cancer biology and drug interactions.
Western Blotting: This technique allows us to analyze protein expression and post-translational modifications relevant to cancer signaling pathways.
Immunofluorescence Staining: We utilize fluorescence-based methods to visualize protein localization and interactions within cells, offering insights into cellular dynamics.
Paraffin Embedding and Tissue Sectioning: These histological techniques are employed for the preparation of high-quality tissue samples for downstream analysis.
Real-time PCR : We perform quantitative gene expression analysis to assess transcriptional changes associated with anti-cancer treatments.
Flow Cytometry: This powerful tool enables us to analyze cell cycle dynamics, apoptosis, and other cellular processes in response to therapeutic compounds.
Xenograft Models: We utilize xenograft techniques to study tumor growth and response to treatment in vivo, providing a critical link between cellular studies and potential clinical applications.